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Fig. 5 | One Health Advances

Fig. 5

From: RNA-based antibiotic susceptibility testing of tmexCD-toprJ-mediated tigecycline resistance in Klebsiella pneumoniae

Fig. 5

RBAST detects different tmexCD1-toprJ1 variants using the selected RNA biomarkers. Heatmap of 12 RNA biomarkers validation across tmexCD-toprJ-negative and different variants of tmexCD-toprJ-positive tigecycline-resistant after tigecycline exposure compared with their own control. The tmexCD-toprJ-negative K. pneumoniae were indicated as ‘S’, and the tigecycline-resistant K. pneumoniae carrying different tmexCD-toprJ variants were indicated as ‘R’. 16S rRNA was applied as the reference gene

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One Health Advances

ISSN: 2731-9970

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