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Fig. 6 | One Health Advances

Fig. 6

From: RNA-based antibiotic susceptibility testing of tmexCD-toprJ-mediated tigecycline resistance in Klebsiella pneumoniae

Fig. 6

RBAST accurately classifies K. pneumoniae isolates. Heatmap of changes in 12 validated RNA biomarkers across tigecycline-susceptible (A) and tmexCD-toprJ-positive tigecycline-resistant (B) K. pneumoniae after tigecycline exposure compared with their own control. Tigecycline-sensitive isolates were indicated as ‘S’, and tmexCD-toprJ-positive tigecycline-resistant isolates were indicated as ‘R’. 16S rRNA was applied as the reference gene

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