Fig. 1

The PLP2 domain is a target of neutralizing antibodies. A Construction strategies for prokaryotic expression of truncated nsp2 proteins. B SDS-PAGE analysis of the purified nsp2 proteins. C The antibody absorption assay. The hyper-immune serum was absorbed by nsp2 derivatives or by nsp9, followed by NA titration in MARC-145 cells. Error bars represent standard deviation (SD). Asterisks (*) mean the statistical difference (*, P < 0.05; **, P < 0.01; ***, P < 0.001)